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By consuming vitamin B6 in the active P5P form, conversion is no longer necessary, and the full benefits are available immediately after absorption.


(Pyridoxal-5-PhosphateActivated form of Vitamin B6)

Pyridoxal-5-Phosphate, or P5P as it is commonly known, is the active form of vitamin B6.  In foods or most supplements, vitamin B6 is found in one of three forms: pyridoxine hydrochloride, pyridoxal, or pyridoxamine.  Inside the body, these forms of B6 have to be converted by the liver to the active form the body needs – P5PLow rates of conversion from the inactive to the active form of vitamin B6 have been reported, especially in people with impaired liver function, celiac’s disease, older adults, and in children with autism.  By consuming vitamin B6 in the active P5P form, conversion is no longer necessary, and the full benefits are available immediately after absorption.

Vitamin B6, in it's P5P form, assists in an amazing variety of tasks – the creation of heme, the iron-containing component of red blood cells; making the hormone serotonin (the “feel good” hormone); processing carbohydrates for energy; keeping the nervous system working smoothly, and supporting hundreds of other jobs.  A deficiency in vitamin B6/P5P can lead to fatigue, and a weakened immunity system. 

P5P supports the use of magnesium in the body, and the two have such a positive influence at such a basic level.  Deficiency of  these two powerful nutrients can cause a host of health related issues.  P5P, combined with magnesium, has shown to reduce the risk of heart attacks up to 70%, significantly reduces morning sickness in pregnancy, helps prevent complications of diabetes, reduces arthritis symptoms, promotes healthy skin, and fights off many other health conditions.   Being deficient in P5P has significantly shown to cause mental health issues such as depression.  Many individuals who have complained of "mental fog" and confusion, have been shown to be severely deficient in P5P.  After P5P therapy, most subjects showed a profound increase in mental clarity. 

Many other symptoms of low P5P include: 

  • Anxiety and Irritability

  • Brain Fog and Memory

  • Depression

  • Chronic Fatigue including Muscle Weakness

  • Low Libido

P5P and Testosterone

P5P works to decrease estrogen levels in the body, which of course help testosterone levels rise.

P5P also works with androgen production, leading to to increased testosterone levels. 

Being deficient in P5P can show decreased levels of Testosterone.   The P5P form of Vitamin B6, coupled with magnesium glycinate chelate (yes, the type used in FREE-T-UP), can make a profound difference in your overall health, including your hormonal health. 


P5P may naturally cause your body to produce more testosterone. This increase of testosterone promotes muscle cell growth.  As stated earlier, P5P helps amino acid breakdown and protein synthesis.  In simpler terms, it allows proteins to be used to grow muscle tissue.  But it has even further effects on the metabolism of other macro-nutrients, specifically carbohydrates.   P5P has been shown to significantly increase carbohydrate uptake for energy vs fat gain in the human body.  P5P is a must in your metabolism performing at peak levels. 


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